COMBINED LIPIDOMIC AND PROTEOMIC ANALYSIS OF ISOLATED HUMAN ISLETS EXPOSED TO PALMITATE REVEALS TIME-DEPENDENT CHANGES IN INSULIN SECRETION AND LIPID METABOLISM.

Studies on the pathophysiology of type 2 diabetes mellitus (T2DM) have linked the accumulation of lipid metabolites to the development of beta-cell dysfunction and impaired insulin secretion.In most in vitro models of T2DM, rodent islets or beta-cell lines are used and typically focus is on specific cellular pathways or organs.Our aim was to, first

The aim of this paper is to outline how physical education taught at special schools intended primarily for children with mild intellectual disability has evolved.The institutions in question are special schools (officially referred to as "practical elementary schools"), which have existed since 1948.Research of both historical and contemporary leg

Recently, remote sensing (RS) technology are becoming an increasingly important technology in estimating forest growing stem volume (GSV), and the saturation issue of spectral variables from various optical sensors severely hinders the Pan improvement of mapping forest GSV, especially in the planted forest with high GSV.Forest canopy height is wide

Traditional disease severity monitoring is subjective and inefficient.This study employs a Parrot multispectral sensor mounted on an unmanned aerial vehicle (UAV) to apply machine learning algorithms, such as random forest, for categorizing defoliation levels in R7-stage soybean plants.This research assesses the effectiveness of vegetation indices,

Objective: To optimize rapid clinical recovery and restoration of function and functionality, permissive weight-bearing has been designed as a new aftercare mobilization regimen, within the upper boundary of the therapeutic bandwidth, yet safe enough to avoid overloading.The aim of the present paper is to describe a comprehensive protocol for permi